tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate in the intermediate of Rosuvastatin.
(4R-cis)-6-aldehyde -2,2-dimethyl -1, 3-dioxane-4-butyl acetate is an important intermediate in the synthesis of the hypolipidemic drug rosuvastatin calcium (RosuvastatinCalcium). Rosuvastatin calcium is the latest statin drug approved by AstraZeneca in Europe in 2002. It is a "super statin" evaluated by the media and is by far the most powerful lipid-lowering drug. For the treatment of primary, familial hypercholesterolemia and mixed lipid abnormalities.
