Semaglutide main chain P29 and Semaglutide side chain (tetrapeptide) are Semaglutide N-3 main chain intermediate and N-3 fragment. TheSemaglutide main chain P29 was acylated with Semaglutide side chain to obtain Semaglutide primary acylation intermediate. Further reaction was underwent to obtain the final API. These products are suitable for for the enterprises that have the production capacity and want to own the API approval. Acylation, hydrolysis tank, high pressure chromatography system, drying equipment are required.
