2,4-diamino-6-(hydroxymethyl)-pteridine hydrochloride is used as intermediate of Methotrexate.
Nature:
-Appearance: White or off-white crystalline powder
-Melting point: about 280-285°C
-Formula: C8H12N6O2 • HCl
-Molecular weight: 274.68g/mol
-Soluble: Dissolved in waterUse:
-Pharmaceutical field: 2,4-diamino-6-(hydroxymethyl)-pteridine hydrochloride is an important organic synthesis intermediate that can be used to synthesize various biologically active molecules and pharmaceutical compounds.
-Laboratory research: It is also often used as a probe molecule in biochemical experiments.
Preparation Method:
2,4-diamino-6-(hydroxymethyl)-pteridine hydrochloride is prepared by adding an appropriate amount of 2,4-diamino-6-(trimethoxymethyl) pteridine hydrochloride in ethanol, adding a certain amount of ammonia water, and carrying out reaction, crystallization and purification.
Safety Information:
-In the operation, should follow the safety procedures, such as wearing gloves and protective glasses.
-Avoid contact with skin and eyes. If accidental contact occurs, rinse immediately with plenty of water.
-Need to store in a dry, well-ventilated place, away from combustibles and oxidants.
-If ingested or inhaled, seek medical attention immediately.
