2-Chloro-5-fluoronicotinonitrile is an intermediate of Vericiguat.
Is an organic compound with the chemical formula C6H2ClFN2. The following is a description of its nature, use, formulation and safety information:Nature:
-Appearance: White solid or crystalline.
-Melting point: about 82-86 ° C.
-Boiling point: About 238-244 ° C.
-Solubility: Soluble in organic solvents, such as ethanol, ether.
Use:
-Chemical intermediates: As an important intermediate in organic synthesis, it can be used in the synthesis of various drugs and pesticides.
-Pesticides: Its derivatives are often used as pesticides for agricultural protection.
Method:
Synthesis can generally be achieved through the following steps:
1. 2-Chloro-5-fluoropyridine reacts with sodium cyanide in alcohol.
2. The product was obtained by filtration and then purified by crystallization.
Safety Information:
-is an organic compound and should be handled in strict accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, goggles and protective masks.
-Avoid inhaling its vapors and maintain good ventilation during operation.
-If ingested by mistake or inhaled, consult a doctor immediately and show the container or label to the doctor.
-Waste disposal: Local regulations should be followed and do not dump into water bodies or the environment.
